life extension ashwagandha
2005 Jun 3;99(2):165-78. Maity T, Adhikari A, Bhattacharya K, et al. Discover nutrients you need for optimal health, Stay informed with Life Extension Magazine, From basic health panels to genetic testing, 1-800-226-2370 -ThisserviceisFREE8-1 AM Mon-Fri | 9-1 AM Sat-Sun (ET). It is this type of cellular degeneration that can lead to long-term cognitive difficulties. Pregnenolone appears to be a neuroprotectant, defending the brain from various forms of injury. What does it mean to support healthy brain cells? Andrew Davis, Health & Wellness Writer. It includes the highest bioavailable withanolide content available for stress, sleep, and anxiety support. All rights reserved. Optimized Ashwagandha Extract, 60 vegetarian capsules - Life Extension Vitamins & Supplements Stress Management Optimized Ashwagandha Extract Click to Zoom Best Seller Optimized Ashwagandha 60 vegetarian capsules Item # 00888 Promotes a healthy response to stress 4.8 261 Reviews | Write a review Don't let stress weigh you down. Preclinical studies have shown that ashwagandha: Animal models of Alzheimer's also show a drop in two key proteins associated with brain maintenance and repair: brain-derived neurotrophic factor (BDNF) and glial fibrillary acidic protein (GFAP). Some people also use ashwagandha for improving thinking ability, reducing pain and swelling, and to increase libido, says Bah. Pregnenolone, a hormone and hormone-precursor, as well as the derivatives it forms in the brain, have modulatory effects on nervous system function. Our Optimized Ashwagandha delivers a standardized extract of Withania somnifera, an Ayurvedic herb known to help relieve the effects of everyday stress. Enable collaborative features and customize widget: An error on our end has caused the item you were trying to add to your cart to fail, please try again or call, Ashwagandha has been hailed for its potential benefits, promote already-healthy levels of cortisol, testosterone levels in men drop 1.6% each year, https://pubmed.ncbi.nlm.nih.gov/19501822/, https://pubmed.ncbi.nlm.nih.gov/23439798/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2544367/, https://www.webmd.com/vitamins/ai/ingredientmono-953/ashwagandha, Ahmad, Mohammad Kaleem et al. Suffice to say, the buzz is well-earnedif anything, that copious praise is an understatement! Organic Ashwagandha and Organic Blueberries to support well-being and improve overall quality of life. Whether you're thinking about taking a new multivitamin or a powerful herb like ashwagandha, your doctor is your partner in good health, and it's always a good idea to run any tweaks to your wellness routine by an expert. All rights reserved. According to studies I've read what really matters is the amount of Withanolide contained in Ashuwangada. Chem Pharm Bull (Tokyo). Normal levels of glutamate are vital to brain communication.4, But very high levels of glutamate can cause excitotoxicityoverstimulation of brain cells that can cause them to go haywire, and even die. Price at time of publish: $40 for 60 count, Type: Tablet | Key Ingredients: Ashwagandha, jatamansi, licorice root, gotu kola, dwarf morning glory|Age Range:10+ |Dosage:1-2 tablets twice daily |Certified:ISO, GMP. Medical doctors, nutritionists & other health professionals are passionate about providing personalized solutions to help you achieve optimal health. When should you take ashwagandha supplements? Published by Life Extension Ashwagandha, an exotic Indian herb, has remarkable stress-relieving properties comparable to those of powerful drugs used to treat depression and anxiety. I was taking another brand and decided to test Life Extension because I have been consuming a lot of products from this respected brand for a long time. Govindarajan R, Vijayakumar M, Pushpangadan P. Antioxidant approach to disease management and the role of Rasayana herbs of Ayurveda. When it comes to choosing an ashwagandha supplement,Kimberly Snyder, a plant-based nutritionist and holistic wellness expert, says that first and foremost, you want to make sure it has theUSDA organic stamp. "Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions. Ease of Use. If youre looking to consume ashwagandha for general health promotion, its recommended to take it on an empty stomach in the morning, says Snyder. 2015;31(6):781-786. doi: 10.1016/j.nut.2014.10.014. Please subscribe to get email updates on this blog. Snyder also recommends looking for supplements that contain the whole herb rather than herb extractions. Neurosignals. They cross the blood-brain barrier and enter brain tissue, where they can exert beneficial actions.11,12, In healthy adults, ashwagandha taken daily has been shown to improve cognitive performancewith boosts in reaction time, discrimination, vigilance, and other tests of brain function.5, Nearly 10% of American adults suffer from mood disorders like anxiety, depression, and bipolar disorder in any given year.13. 14. Price at time of publish: $20 for 60 count, Type: Capsule | Key Ingredients:Organic ashwagandha powder, organic ashwagandha extract, organic ashwagandha supercritical C02 extract |Age Range:Adult 18+ |Dosage:1 capsule |Certified:USDA organic, non-GMO, GMP, Good Laboratory Practice Certification, Manufacturing facility also processes fish extracts, Many ashwagandha supplements sell online, but heres one you may be able to find in your local drugstore. Life Extension, Optimized Ashwagandha, 60 Vegetarian Capsules - iHerb.com Zahiruddin S, Basist P, Parveen A, et al. Ashwagandha is a powerful root extract, but always speak with your doctor before incorporating new supplements into your wellness routine. While further human studies are needed, these findings suggest that ashwagandha may be an excellent adjunctive therapy to chemotherapy.19. I like adding it to turmeric lattes when I'm winding down in the evening. This scientifically proven formula is made with100 percent pure extracts of ashwagandha, says Faatimah Bah, a dietitian in Saudi Arabia. The herb ashwagandha improves brain function and may defend against cognitive decline. Capsule. "As with any herbal or medicinal supplement, the longer it's exposed to air and sunlight, the less effective it will be, says Lorencz. Rajasankar S, Manivasagam T, Surendran S. Ashwagandha leaf extract: a potential agent in treating oxidative damage and physiological abnormalities seen in a mouse model of Parkinson's disease. These products are recommended based on your quiz answers. In order for you to enjoy all the health benefits ashwagandha offers, like helping maintain already-healthy cortisol levels and fighting fatigue, you need a high-quality product. Life Extension does not provide medical advice, diagnosis, or treatment. Note that ginkgo is a blood thinner, so discuss with your doctor before taking this supplement. Our Optimized Ashwagandha delivers a standardized extract of Withania somnifera, an Ayurvedic herb known to help relieve the effects of everyday stress. Its on NOW! What are the benefits of ashwagandha supplements? Ashwagandha has been hailed for its potential benefits for memory, vitality, hormone function, weight management and the nervous system. Plus, ashwagandha has been linked to better exercise performance and endurance. There have not been enough long-term studies to fully examine any long-term side effects of ashwagandha root, but it is important to stick to the dosage on the bottle as excessive amounts may lead to side effects. More information at www.consumerlab.com/survey. ChronoscreenTM Analysis: Cognition Enhancing Drugs & Natural Extracts. Tohda C, Kuboyama T, Komatsu K. Search for natural products related to regeneration of the neuronal network. The participants subjectively reported increased energy, reduced fatigue, better sleep, and an enhanced sense of well-being. Extra 25% off when you subscribe. Many degenerative diseases, as well as premature aging, are associated with chronic nervous tension. 2004 Nov;52(11):1358-61. Khalid S, Barfoot KL, May G, et al. I chose this Life Extension product based on the Sensoril formulation of this ashwagandha product, Life Extensions reputation of good products, and reviews from others here at Amazon. J Ethnopharmacol. Note that when using these products, or any type of supplement, its important to consult your doctor for proper dosing information, especially if you are pregnant and/or breastfeeding, or have been diagnosed with an autoimmune disease. To date, scientists have identified and studied at least 12 alkaloids and 35 withanolides. Also supports an exhausted nervous system by supporting the adrenal glands that respond to stress. Ashwagandha has been used in Ayurvedic medicine to help promote energy, support overall health, help promote healthy stress response and support blood pressure already within a normal rangeit is thought to accomplish all of these whole-body benefits because of its calming effects to the nervous system. Life Extension, Optimized Ashwagandha, 60 Vegetarian Capsules By Life Extension 5477 Reviews | 31 & 187 Roll over image to zoom in In Stock Best By: February 1 2025 Date First Available: April 15 2009 Shipping Weight: 0.1 lb Product Code: LEX-88806 UPC Code: 737870888062 Package Quantity: 60 Count Dimensions: 3.5 x 1.9 x 1.9 in, 0.1 lb Andrew Davis is a graduate of Pace University NYC with a Bachelor of Arts in Psychology. Sangiovanni E, Brivio P, Dell'Agli M, et al. By 6:30 I had lost my appetite, felt shaky, and had been in my bathroom peeing for 45minutes. Supporting cognition, memory, healthy stress response, and overall well-being. 2005 Apr;144(7):961-71. I love this supplement, whichcomes in powder form and can be easily added to smoothies, lattes, or other warm drinks, says Gena Hamshaw, RD, a registered dietitian in New York City and author ofThe Full Helpingblog. Ashwagandha reduces stress and anxiety, and relieves symptoms of depression. Effect of Withania somnifera Dunal Root Extract on Behavioral Despair Model in Mice: a Possible Role for Nitric Oxide. When test animals received a common chemotherapy drug, levels of the desirable immune factors interferon-gamma and interleukin-2 decreased. Scientifically Reviewed By: Involvement of hippocampal Arc in amnesia and its recovery by alcoholic extract of Ashwagandha leaves. Choudhary MI, Yousuf S, Nawaz SA, Ahmed S, Atta uR. 2005;10(2):85-87. The participants taking ashwagandha also had improvements in physical parameters related to stress such as stress-related muscle tension.2 Again, at the higher doses, greater improvements were seen. This finding suggests that ashwagandha could help heal the brain tissue changes that accompany dementia.6, Finally, in a third published study, the researchers noted that ashwagandha helped promote the growth of both normal and damaged nerve cells, suggesting that the herb may boost healthy brain cell function as well as benefit diseased nerve cells.7. Optimized Ashwagandha Extract, 60 vegetarian capsules - Life Extension Wonderful Ashuwangada! Ratings based on results of the 2023 ConsumerLab.com Survey of Supplement Users. All Contents Copyright 2023 Life Extension. Amazingly, when ashwagandha was administered to chronically stressed animals, the number of degenerating brain cells was reduced by 80%!3, In one of the most complete human clinical trials to date, researchers studied the effects of a standardized extract of ashwagandha on the negative effects of stress, including elevated levels of the stress hormone cortisol. Withania somnifera reverses Alzheimer's disease pathology by enhancing low-density lipoprotein receptor-related protein in liver. Buy Life Extension Optimized Ashwagandha Extract | LiveHelfi An Overview on Ashwagandha: A Rasayana (Rejuvenator) of Ayurveda., Stanworth, Roger. 17. | FREE SHIPPING on orders $50+. Ashwagandha is a powerful male health herb because it may help keep testosterone production within a normal, healthy range, supporting healthy hormone balance. Research shows ashwagandha works to reduce stress, in part, because the herb reduces activity in one's HPA axis the part of the brain in charge of regulating stress response. 449. Life Extension Ashwagandha 4. Scholey AB, Tildesley NT, Ballard CG, et al. This important research may one day benefit those who have incurred brain injuries due to physical trauma, as well as those who suffer cognitive decline due to destruction of the nerve cell networks from diseases such as dementia and Alzheimers. If you know of one we should consider, please email us atcontact@byrdie.comand we will evaluate the product ASAP. A dedicated ashwagandha regimen may also help promote healthy fertility in men. More information at www.consumerlab.com/survey. Life Extension Magazine Ashwagandha's Brain Benefits The herb ashwagandha improves brain function and may defend against cognitive decline. Its on NOW! And that's not all! Moon Juice is well-known for their adaptogen supplements and skincare, and this ashwagandha supplement is one of their best-selling products. From a tough commute to a spat with a family member, our already-cortisol levels are at the mercy of these daily ups and downs, and influence how our nervous system functions with the rest of our body. The herb is classified as an adaptogen, which indicates its capability to normalize physiologic processes and thereby stabilize the body's response to stress. Scientists speculate that some of ashwagandhas benefits stem from its antioxidant properties and ability to scavenge free radicals.10, Two main classes of compoundssteroidal alkaloids and steroidal lactonesmay account for its broad range of beneficial effects. Neuroprotective effects of Withania somnifera in BPA induced-cognitive dysfunction and oxidative stress in mice. Here is everything you need to know about ashwagandhaand why this powerful adaptogenic herb deserves a spot in your wellness routine. A Randomized, Double-Blinded, Placebo-Controlled Study to Compare the Safety and Efficacy of Low Dose Enhanced Wild Blueberry Powder and Wild Blueberry Extract (ThinkBlue) in Maintenance of Episodic and Working Memory in Older Adults. An avid traveler, Andrew also has volunteered as an English teacher and humanitarian in countries throughout Asia. It would appear from this study that ashwagandha can address many of the health and psychological issues that plague todays society.4. While ashwagandha is an ancient herb, its long-term benefits have not been studied in researchnor have side effects been identified clinically. 2,004. Scientifically reviewed by: Gary Gonzalez, MD, in May 2021. Effects of a standardized extract of Withania somnifera (Ashwagandha) on depression and anxiety symptoms in persons with schizophrenia participating in a randomized, placebo-controlled clinical trial. 2006 Jan 9. Here's where ashwagandha comes inthis herb has been shown to promote healthy levels of cortisolwhich may specifically help when faced with "fight or flight" situations. The participants showed several measurable improvements, including a reduction of cortisol levels up to 26%, a decline in fasting blood sugar levels, and improved lipid profiles. stress anxiety fatigue pain skin conditions diabetes arthritis epilepsy Different treatments make use of different parts of the plant, including the leaves, seeds, and fruit. Mukherjee S, Kumar G, Patnaik R. Withanolide a penetrates brain via intra-nasal administration and exerts neuroprotection in cerebral ischemia reperfusion injury in mice. Ashwagandha, an exotic Indian herb, has remarkable stress-relieving properties comparable to those of powerful drugs used to treat depression and anxiety. She specializes in plant-based nutrition and is one of the most recognized nutrition experts in America. Your cortisol levels are higher in the morning, helping you to jumpstart your body for the day ahead, and will later drop at night when it is time to unwind. Several recent trials in humans have demonstrated that blueberries enhance cognitive function. Supports a healthy response to everyday stress, Encourages already-healthy levels of the stress hormone cortisol. Enter your email address if you would like your recommendations emailed to you. Learn Ingredients Ashwagandha Ashwagandha Ashwagandha (Withania somnifera) has been called the king of ayurvedic herbs. Some brain injuries, such as traumatic head injuries and stroke, cause a huge release of glutamate that results in further cell death.4, Glutamate excitotoxicity has been found to be a component of the pathology seen in neurodegenerative disorders, such as Alzheimer's disease, Parkinson's disease, ALS, and multiple sclerosis.4, Ashwagandha defends the brain against this damage. As a supplement, it has been shown to support the bodys stress response, which is a very common cause of restless nights, she says. Life Extension Launches Rest & Renew Ashwagandha (Withania somnifera) has an extensive history of use in Indian Ayurvedic traditions, where it is used to promote healthy energy, emotional balance, and memory health.1 Our Optimized Ashwagandha provides 125 mg of standardized Sensoril Ashwagandha Extract per serving. 21. Ashwagandha also helps keep hormones in balance. All rights reserved. Price at time of publish: $86 per 60 count, Type: Capsule | Key Ingredients:Ashwagandha, acetyl-L carnitine, ginkgo phytosome, bacopa extract, pterostilbene, caffeine, lutein, zeaxanthin isomers |Age Range:Adult 18+ |Dosage:2 capsules |Certified:cGMP certification from NSF International, Contains highest concentration of withanolide available. Feeling out of sorts? Please subscribe to get email updates on this blog. In lab studies, pretreatment with ashwagandha extracts before exposure to high levels of glutamate markedly inhibit cell death and other changes associated with excitotoxicity.1,32,33. Byrdie takes every opportunity to use high-quality sources, including peer-reviewed studies, to support the facts within our articles. In several animal studies of experimental stroke, ashwagandha intake prevented much of this brain damage.34-38 It reduced the size of the brain injury and the biochemical changes that typically accompany stroke. Men's testosterone levels decrease over timethis is a normal part of the aging process. It contains both the root and leaf, and 10 percent withanolide, so its very potent, she adds. This remarkable herb also grows new nerve cells and inhibits the growth of human breast, lung, colon, and other cancer cells. Take one (1) capsule twice daily on an empty stomach, or as recommended by a healthcare practitioner. Ashwagandha also shows promise as a treatment for Parkinsons and Alzheimers diseases, chronic neurodegenerative conditions for which there currently are no cures. So Life Extension the science-based supplement company has launched a formula to help sleepers prioritize quality rather than just quantity; this melatonin-and-ashwagandha combination is called . In recent years, ashwagandha's benefits have been championed in the media, making it a relevant and popular dietary supplement even in the 21st century. Hum Exp Toxicol. Indeed, the powder form the ashwagandha root has been clinically studied to support already-healthy blood sugar levels, possibly because it appears to promote healthy insulin metabolism. 1. It contains nutrients needed to restore proper sleep-wake cycles and to help improve both sleep quality and quantity. 60 Count (Pack of 1) 1,562 600+ bought in past week $750 ($0.13/Count) List: $10.00 $7.13 with Subscribe & Save discount 2015 Jun;31(6):781-6. A systematic review of the clinical use of Withania somnifera (Ashwagandha) to ameliorate cognitive dysfunction. Ashwagandha has also shown promise in preclinical studies of other neurodegenerative diseases, including Parkinson's disease, amyotrophic lateral sclerosis (ALS), and Huntington's disease.1,2,28,29, Ashwagandha has been found, in preclinical models, to shield against a range of neurotoxins, including lead, aluminum chloride, streptozotocin, scopolamine, kainic acid, and bisphenol A (BPA, a common additive in plastics).1,30,31, One example is glutamate.
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