curcumin topical cream
On the other group, individuals were administered a topical moisturizer cream as the . Br J Dermatol. There appears to be at least two important reasons for this. Aggarwal BB, Gupta SC, Sung B. Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers. (2015) Curcumin-induced angiogenesis hastened wound healing in diabetic rats. J Surg Res 193: 978-988. Curcumin at 15 mg administered by oral, topical, or combined formulation significantly reduced tumor growth compared to control (P = 0.004). Please reach us at sales@psoria-gold.com if you cannot find an answer to your question. She had good graft survival and the scar healed with minimal scarring (Figure 5, right panels). [4], reported that in 2015, the Curcumin Resource Database listed over 9000 publications and 500 patents on potential therapeutic value curcumin for a number of unrelated diseases. (2004) Temporal patterns of gene expression in murine cuitaneous burn wound healing. both serine/threonine and tyrosine. Link: Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, et al. J Dermatol Res Ther. One limitation of curcumin is its poor bioavailability, due to its low solubility in water and low stability. Int J Dermatol 52: 531-543. Georgoussi et al., has reported that phosphorylase kinase also exhibits phosphatidylinositol kinase activity [14]. Curcumin may also have potential interactions with certain medications such as . Photo-damaged skin: Actinic dermatitis and keratosis: Figure 10a (upper panel) shows photo-damaged skin (actinic dermatitis) with multiple confluent actinic keratoses involving the ear. Mat Sci Eng C Mater Biol 69: 1183-1191. Evidence of Curcumin and Curcumin Analogue Effects in Skin Diseases: A Narrative Review. Journal of Cellular Physiology 234 (2): 116578. active oral tablet plus active topical gel; 2.) Check your spam (bulk mail) folder. Epub 2023 Mar 30. By slowing down the energy supply to the inflammatory processes, curcumin targets multiple NF-kB-dependent pathways, with salutary effects on skin disorders induced by injury. How Could Turmeric Prevent or Treat Prostate Cancer? Psoria-Gold owns its own well which draws its water from deep aquifers and springs. Turmeric for Eczema: Does It Work? - Healthline Burns from a Barbeque Fire: Figure 2a shows a patient who sustained secondary degree burns after pouring lighter fluid on a barbeque fire. The glucosamine/chondroitin preparation was a water soluble cream containing glucosamine sulphate {3.0 mg/g} , chondroitin sulphate {7.2 mg/g} , and shark cartilage {14 mg/g} , of which 10-30% is chondroitin sulphate, camphor (32 mg/g), and scented with peppermint oil (9 mg/g). of Complementary Medicine, Postgraduate Medical School, University of Exeter 13 (1): 2223. Topical curcumin-based cream is equivalent to dietary curcumin in a Or if you are still concerned, just call us at (888) 776-7421 and leave a message, or email us at, Yes! Peter A. Lio, MD is a Clinical Assistant Professor of Dermatology and Pediatrics at Northwestern University Feinberg School of Medicine and a partner at Medical Dermatology Associates of Chicago. It is thought to be extensively metabolized, leaving little curcumin to be absorbed. 4 The main purpose of this study was to isolate curcumin from the Curcuma longa plant and formulate herbal cream containing . Curcumin (diferuloylmethane) is one of the ingredients found in the spice, turmeric. Methods:A randomized double-blind, placebo-controlled study including 63 breastfeeding women with lactational mastitis were randomly assigned to receive curcumin topical cream, one pump every 8 hours for 3 days (n=32) or topical moisturizer as placebo (n=31). Plus, get the free bonus report, Mother Natures Tips, Tricks and Remedies for Cholesterol, Blood Pressure & Blood Sugar as my way of saying welcome to the community! Chang, Anne Lynn, and Claudia Munoz. Turmeric for Fibromyalgia and Chronic Fatigue Syndrome, Turmeric, The Golden Spice: From Traditional Medicine to Modern Medicine, Curcumin: A Review of Its Effects on Human Health, Turmeric tonic as a treatment in scalp psoriasis: A randomized placebo-control clinical trial, A Review of Scabies: An Infestation More than Skin Deep. Turmeric, Curcumin, and Curcuminoids: A Dermatologic Review Various topical formulations are investigated by researchers around the world for . Before you visit the Psoria-Gold Online Shop, here are some answers to frequently asked questions that may help you navigate through the ordering process. Topical application of curcumin contributes to granulation (healing at the edges), new tissue formation, collagen deposition (increases the strength of the wound), tissue remodeling (restores the characteristics of the tissues), and wound contraction (reduces the size of the wound). 2000 Nov;143(5):937-49. Epub 2012 Aug 13. Specifically, curcumin has been shown to potentially play a role in type 2 diabetes mellitus by reducing lipid levels, in metabolic syndrome by increasing insulin sensitivity and production, in cardiac diseases by lowering C reactive protein, and even in major depressive disorder via its anti-inflammatory effects. 2018 Jan-Feb;84(1):16-21. doi:10.4103/ijdvl.IJDVL_1143_16, Chandler DJ, Fuller LC. Nine studies evaluated the effects of ingestion, eight studies evaluated the effects of topical, and one study evaluated the effects of both ingested and topical application of turmeric/curcumin. Despite these findings, turmeric has been difficult to use topically due to its bright yellow color and characteristic odor. Please view the refund process on our, Consolidating shipping days to two days a week. Jill S. Waibel, MD; and Joel Schlessinger, MD, FAAD, Conjunctival Squamous Cell Carcinoma: A Video-Illustration of a Surgical Approach, Anoushka Gidh; Megan Ruben; Antonio Yaghy, MD; and Carol L. Shields, MD, Andrea M. Rustad, BA; Melissa A. Nickles, BA; and Peter A. Lio, MD, Lori S. Kim, BA; Anar Mikailov, MD; and Peter A. Lio, MD. PMC 2021;61(20):3421-3435. doi: 10.1080/10408398.2020.1798353. We are happy to assist you if you have trouble placing an online order, or you made a mistake on your last order. Vaughn AR, Clark AK, Notay M, Sivamani RK. In addition, the substrate binding site may be made to alter its shape and swivel in one plane by binding to magnesium, or in another by binding to manganese. Curcumin: A Review of Its Effects on Human Health. By inhibiting phosphorylase kinase in the injury pathway, curcumin blocks the activation of NF-kB, the transcription activator [5,19,20]. Curcumin, the active ingredient in the spice, turmeric, is a selective, non-competitive phosphorylase kinase inhibitor. Yang Y, Su Y, Yang H, et al. The effectiveness of oral curcumin, however, is hindered by poor bioavailability because the unconjugated curcumin molecule, which is hydrophobic, is poorly absorbed by the gastrointestinal tract. Kant V, Gopal A, Pathak NN, Kumar P, Surendra KT, et al. Do I have to create an account to place an order? The range of skin conditions that appear to respond to use of topical curcumin suggests that more than one mechanistic effect may be operating with topical curcumin use, i.e. Normally Turmeric found at the altitude of 500-900 m in Thailand. Potential of Curcumin in Skin Disorders. Nutrients 11 (9). Probably more importantly, oral curcumin is poorly absorbed and has very low bioavailability, which essentially renders curcumin a poor candidate as an effective oral agent [1-3]. Int J Biol Macromol 98: 268-276. However, currently published studies are limited and further studies will be essential to better evaluate efficacy and the mechanisms involved. (2017) Nano-encapsulation, a efficient and promising approach to maximize wound healing efficacy of curcumin: a review of new trends and state-of-the-art. 2019 research confirmed that curcumin may help control the mechanisms involved in inflammation and infectious skin disorders. This site needs JavaScript to work properly. Dermatology. Skin conditions examined include acne, alopecia, atopic dermatitis, facial photoaging, oral lichen planus, pruritus, psoriasis, radiodermatitis, and vitiligo. Before He is a clinical professor at the University of Colorado in Denver, and co-founder and practicing dermatologist at the Boulder Valley Center for Dermatology in Colorado. While curcumin is generally considered safe to use, some negative side effects, including headache, nausea, diarrhea, rash, and yellow stool, have been reported. Pakfetrat M, Basiri F, Malekmakan L, Roozbeh J. Link: Heng MC, Song MK, Harker J, Heng MK (2000) Drug-induced suppression of phosphorylase kinase activity correlates with resolution of psoriasis as assessed by clinical, histological and immunohistochemical parameters. It is a well-known natural topical anti inflammatory, but lesser known is its ability to inhibit the release of Phosphorylase Kinase (Ph-K), the enzyme which initiates unwanted skin appearances upon onset of injury. 2018 Jan 21;6(1):218-220. doi:10.3889/oamjms.2018.055, Akbik D, Ghadiri M, Chrzanowski W, Rohanizadeh R. Curcumin as a wound healing agent. Photomed Laser Surg 29: 809-814. J Cell Biol 186: 835-847. Turmeric contains a key ingredient called curcumin. Topical Curcumin may have Pleotropic Effects: In the cases above, we showed clinical benefits of topical curcumin in a fairly diverse variety of dermatologic conditions, including heat related injuries, solar damage and burns, skin wounds, skin healing after surgery, and chronic inflammatory skin conditions like psoriasis, acne, and rosacea. There is evidence that phosphorylase kinase also activates phosphatidylinositol kinase [14]. Trial registration Jain SK, Rains J, Croad J, Larson B, Jones K. Curcumin Supplementation Lowers TNF-, IL-6, IL-8, and MCP-1 Secretion in High Glucose-Treated Cultured Monocytes and Blood Levels of TNF-, IL-6, MCP-1, Glucose, and Glycosylated Hemoglobin in Diabetic Rats. Antioxidants & Redox Signaling 11 (2): 24149. In her research, she was able to significantly help psoriasis sufferers with a combination of topical curcumin, topical corticosteroids and the elimination of certain phosphorylase kinase-promoting elements (like bacteria, allergens, fungi, etc.). To overcome this limitation, current studies are investigating nanotechnology, such as liposomes-phospholipid, nanogels, nanostructured lipid carriers, nanoemulsions, polymeric micelles, and various polymeric nanoparticulate methods to deliver curcuminoids. Psoriasis. Complete repigmentation occurred after topical . Euden SA, et al. Or if you are still concerned, just call us at (888) 776-7421 and leave a message, or email us at sales@psoria-gold.com. Curcumin and its topical formulations for wound healing applications If youre unable to find a topical curcumin or turmeric product that fits your budget and preferences, dont worry. J Biol Chem 268: 17683-17686. She was also put on oral Diflucan 200 mg weekly for candida intertrigo, lactose free diet and daily bleach baths. Turmeric: 6 Ways It Benefits Your Skin - Verywell Health Acne. Curcumin (diarylheptanoid) is one member of a group of natural compounds called curcuminoids, derived from the rhizome of Curcuma longa, an East Indian plant, contained in an extract commonly called turmeric. In HT-29 cell. The water we use in all our products is then further purified and deionized. It may also affect the immune system cells that are in part responsible for eczema. (2015) Curcumin, a golden spice with low bioavailability. Anticancer Res 23: 363-398. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. For control of the pustules, she was put on oral minocycline 100 mg daily. We have quarterly sales on a regular basis. National Center for Complementary and Integrative Health. However, essential oils that have antimicrobial properties have also been used. Another limitation is the small placebo group, which started with two participants, but only one completed the study. Both groups showed statistically significant improvement in subjects subjective rating of pruritus, and there was no significant difference between the two groups. Psoria-Goldis intended for cosmetic and topical use only. Panahi Y, Sahebkar A, Amiri M, et al. The research also found that turmeric acid can inhibit T-cell. Newer Strategies involving Nano-encapsulation in Wound healing: Because of its hydrophobic properties, curcumin is known to be poorly absorbed by tissues. Link: Heng MC, Song MK, Heng MK (1994) Elevated phosphorylase kinase activity in psoriatic epidermis: correlation with increased phosphorylation and psoriatic activity. The https:// ensures that you are connecting to the Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review. Why did I not receive an order confirmation? The clinical result is the development of psoriatic lesions that tend to persist rather than heal. Topical application of curcumin regulates the angiogenesis in diabetic Topical Curcumin-Based Cream Is Equivalent to Dietary Curcumin in a The .gov means its official. Turmeric has been used to alleviate several skin conditions, including atopic dermatitis. 6 Benefits of Topical Application of Turmeric In Cancer The curcumin group also showed a statistically significant increase in the antioxidant enzymes superoxide dismutase, glutathione peroxidase, and catalase in comparison to the placebo group. The negative results of clinical trials with oral curcumin are also unlikely to be pertinent to topical curcumin because the pharmacology and therapeutics of oral and topical medications are extremely different. Rawal RC, Shah BJ, Jayaraaman AM, Jaiswal V. Clinical Evaluation of an Indian Polyherbal Topical Formulation in the Management of Eczema. Journal of Alternative and Complementary Medicine 15 (6): 66972. The tip of the little finger was severed. Draganski A, Tar MT, Villegas G, et al. In another study, eight patients were given a curcuminoid preparation orally for 16 weeks, and were evaluated based on Physicians Global Assessment score, Psoriasis Area and Severity Index (PASI), and safety endpoints. Topical formulations of curcumin provide better delivery at wounded sites. The spice turmeric, also known as the golden spice, may have benefits for skin conditions and concerns such as: This spice comes from the turmeric plant. Int J Dermatol 49: 608-622. Crush Injury: The patients fingers of her right hand were crushed by a garage door. Topical application of curcumin . Although we are confident that over the long run, Psoria-Gold products will continue to be the best and most natural option for your skin's health, we understand you may wish to choose another approach. Kant et al. Coupons for future sales are often included in your package. Improvement of Scarring in Acneiform Conditions: Figure 7a (left panels) shows a acne patient with severe follicular plugging. We are happy to assist you if you have trouble placing an online order, or you made a mistake on your last order. 2020 Mar;75:95-108. And 60 percent of these people received long-term remission without any further treatment. Curcumin gel also has been reported to improve the appearance of pigmentary changes due to photodamaged skin conditions (caused by exposure to the sun). The effect of curcumin ointment on knee pain in older adults with Injury Pathway and NF-KB Activation in the Inflammatory Response: The key molecule in the tissue injury pathway (Figure 1) is a transcription activator, nuclear factor-kB, which is expressed as early as 30 mins after injury [15,16]. Neurobiologix Curcumin 4 oz Topical Cream - Topical Vitamin 2007 Aug;14(7-8):437-46. Asawanonda P, Klahan SO. Vaughn AR, Pourang A, Clark AK, et al. Link: Karri VVSR, Kappusamy G, Talluri SV, Mannemala SS, Radhakrishna K, et al. But its probably better to cook with turmeric or take a turmeric supplement than to take a curcumin supplement. There was a statistically significant decrease in radiodermatitis in the turmeric and sandalwood oil cream in comparison to the baby oil. In one animal study, a gel formulation containing 1% curcumin improved psoriasis-like inflammation. Foods. The burns were much improved two days later with frequent applications of topical curcumin (Figure 9b (lower panel). Two participants out of eight achieved 75% improvement in their PASI. Studies showing that curcumin induces apoptosis in damaged cells show yet another aspect of the curcumin pleiotropy [11-14]. The investigators [47] observed that curcumin decreased TNF-, IL-1 and MMP-9, and increased superoxide dismutase and catalases in their animals. Check your spam (bulk mail) folder. Topical Turmeric Microemulgel in the Management of Plaque Psoriasis; A You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. Symptoms include dry, itchy skin, and red rashes that can appear on the scalp, face, hands, and feet. Link: Reddy S, Aggarwal BB (1994) Curcumin is a non-competitive and selective inhibitor of phosphorylase kinase. Psoriasis is an autoimmune skin disorder that produces patches of scaly skin that can itch. (2009) UVA generates pyrimidine dimers in DNA directly. Do you need to boost your love hormone? Two studies tested the efficacy of capsules of a curcumin preparation to treat OLP. If you want to make sure your bodys getting the most from turmeric, make sure to follow the three tips for optimizing your turmeric intake that I shared in another post. In contrast, topical curcumin can be formulated to be better absorbed through the skin, particularly when the skin barrier becomes defective in the presence of skin injury and disease. Link: Yuan CJ, Huang CY, Graves DJ (1993) Phosphorylase kinase: a metal ion-dependent dual specificity kinase. Oral Curcumin in the Treatment of Moderate to Severe Psoriasis Vulgaris: A Prospective Clinical Trial. Journal of the American Academy of Dermatology 58 (4): 62531. Topical Application of a Sandal Wood Oil and Turmeric Based Cream Prevents Radiodermatitis in Head and Neck Cancer Patients Undergoing External Beam Radiotherapy: A Pilot Study. The British Journal of Radiology 87 (1038): 20130490. Other skin-related studies. Hewlings SJ, Kalman DS. In an in-vitro model of psoriasis, curcumin was shown to significantly improve the skin barrier function by upregulating involucrin and filaggrin, which are known regulators of the skin barrier. In a randomized double-blind placebo-controlled trial performed in patients, Afshariani et al. placebo oral tablet plus placebo topical formula. 2022 Oct 6;27(19):6652. doi: 10.3390/molecules27196652. Can Turmeric Help Eczema or Atopic Dermatitis? - Everyday Health Clipboard, Search History, and several other advanced features are temporarily unavailable. [4], suggested As an alternative approach, it may be possible for compound 1 (i.e. It is very rare that we do not receive your order if it has been successfully placed. Link: Kant V, Gopal A, Kumar D, Pathak NN, Nitya NP, et al. Several studies have shown that turmeric and curcumin may provide health benefits for several skin disorders. In studies using mice, for instance, curcumin slowed the activation of potassium channels in T cells, which play a role at the start of psoriasis. Br J Pharmacol. active oral tablet plus active topical cream; 3.) (2009) Nucleotide excision-repair induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response. Link: Wathoni N, Motoyama K, Higashi T, Okajima M, Tatsuo K, et al. Read our, Turmeric for Acne: Possible Benefits, Drawbacks, and Effectiveness, Why You Should Use Turmeric and Black Pepper Together, Ginkgo Biloba: Benefits, Safety, and Dosage, Fennel and Fennel Seeds: A Look at the Benefits, The Many Health Benefits of Turmeric (and Curcumin), Everything You Need to Know About Cardamom, Uses of Lavender: Everything You Need to Know. The Effect of Topical Curcumin Versus Topical Corticosteroid on Management of Oral Lichen Planus Patients: . Various studies have found curcumin to have antioxidant, antibacterial, antifungal, and anti-inflammatory properties, which may help protect sensitive skin. One of the studies measured transepidermal water loss (TEWL) in subjects for four weeks and found that herbal combination tablets significantly decreased TEWL, whereas no significant changes were seen in the turmeric or the placebo groups. Both the interference with assay readout encountered after oral curcumin and low bioavailability were not reported in the context of topical curcumin use. FEBS Lett 341: 19-22. Furthermore, she had normal sensation in the little finger. Support Care Cancer. Phosphorylase kinase is released within 5 minutes following skin injury, and serves as a catalyst for the processes that result in the subsequent activation of over 200 genes responsible for unwanted skin appearance. [36], found topical curcumin to be effective in treating mastitis of breast-feeding women. . In Asian countries, the use of curcumin to treat eczema is a common practice. 10.1002/ptr.5640 Abstract Turmeric (Curcuma longa), a commonly used spice throughout the world, has been shown to exhibit antiinflammatory, antimicrobial, antioxidant, and anti-neoplastic properties. ron glenner says: May 31, 2018 at 10:50 am Excellent anti-Inflammatory. According to some studies, curcumin helps heal wounds by decreasing the body's natural response to skin wounds, like inflammation and oxidation. Link: Afshariani R, Farhadi P, Ghaffarpasand F, Roozbeh J (2014) Effectiveness of topical curcumin of treatment of mastitis in breast-feeding women: a randomized, double-blind, pacebo-controlled clinical trial. Methods Enzymol 99: 268-278. Curcumin (Curcuma, Turmeric) and Cancer (PDQ)-Health Professional Amazon.com: Curcumin Cream 2023 May;72(5):933-945. doi: 10.1007/s00011-023-01724-0. Dr. Heng wrote the paper based on 25 years of research she did in the lab and on her patients. Note: there's an image of ulcerating breast cancer from 3:03 to 3:09 that viewers may find disturbing. It may have been inadvertently directed to spam. In addition, topical preparations can be more easily formulated to increase penetration of the hydrophobic curcumin through the skin, unlike the problems encountered with curcumin bioavailability in the gut. In two other studies, 96 male patients with sulfur mustard-induced chronic pruritus were given either 1g/day of curcumin or placebo capsules for four weeks. Herbal Medicine: Biomolecular and Clinical Aspects. Surgical Wounds and Scars: The patient developed scarring following excision of a basal cell carcinoma situated over the right chin. 54-year-old woman with eczematous reaction to Avon Age Block Environmental Protection Cream (Corby, UK) . Link: Levin MF (2007) ATM and the Mre 11 complex combine to recognize and signal DNA double-strand breaks. Curcumin is thought to downregulate inflammatory targets, such as lipoxygenase, cycloxygenase-2, and inducible nitric oxide synthase. Growing evidence shows that an active component of turmeric, curcumin, may be used medically to treat a variety of dermatologic diseases. Turmeric. We believe that the most likely mechanism responsible for these results is related to the unique ability of curcumin to inhibit the enzyme, phosphorylase kinase. Curcumin for radiation dermatitis: a randomized, double-blind, placebo-controlled clinical trial of thirty breast cancer patients. Colloids Surf B Biointerfaces 150: 223-241. Curcumin has been demonstrated to be an unstable, reactive compound that interferes with assay readout, providing a misleading experimental outcome from this false activity rather than through real compound-target interaction [4]). Curcuminoids Are Not Effective in Oral Lichen Planus. 2008b. J Cosmet Dermatol. He was seen 4 days after sustaining the burns, and was much improved 5 days later (Figure 2b) after topical curcumin use at frequent intervals for the first few days (Figure 2c), and appeared fully healed without detectable scarring two months later. Cancer, Epidemiol, Biomarkers Prev 14: 120-125. PDF Effectiveness of Topical Curcumin for Treatment of Mastitis in It contains the compound curcumin, which has been. active oral tablet plus active topical gel; 2.) Link: Heng MC (2017) Curcumin-induced apoptosis in the repair of photodamaged skin. Please enable it to take advantage of the complete set of features! placebo oral tablet plus placebo topical formula. Oral Lichen Planus. In another study, researchers investigated the effects of a hot water extract of curcumin on human keratinocytes. Di Bartolomeo L, Custurone P, Irrera N, Borgia F, Vaccaro F, Squadrito F, Vaccaro M. Antioxidants (Basel). 2018 Jun;17(3):461-466. doi:10.1111/jocd.12513, Gopinath H, Karthikeyan K. Turmeric: A condiment, cosmetic and cure. The information contained on EasyHealthOptions.com is not intended to be a substitute for professional medical advice or treatment and is for educational purposes only. sharing sensitive information, make sure youre on a federal In this review, we discuss the mechanisms for its anti-inflammatory and anti-apoptotic activity based on its inhibitory activity on the enzyme, phosphorylase kinase, and present evidence for its salutary effects on burns, wounds, surgical scars, photo-damaged skin and psoriasis. (2016) Curcumin loaded chitosan nanoparticles impregnated into collagen-alginate scaffolds for diabetic wound healing. 5% minoxidil; and 4.) For areas which typically experience delivery delays, we highly recommend opting for the $25 extra upcharge using FedEx Express. Turmeric for Eczema: Benefits, Side Effects, Preparations - Verywell Health These findings make curcumin a suitable candidate for treating skin conditions that are characterized by derangement of the inflammatory response. Casey Gallagher, MD, is board-certified in dermatology. Topical curcumin gel effective in treating burns and scalds Jiang Y, Zong Y, Du Y, Zhang M, Ye F, Zhang J, Yang Y, Zhu C, Tang Z. Inflamm Res. In the first study, curcumin 2,000mg/day did not achieve statistical significance in improving clinical severity of OLP in 100 subjects. Crit Rev Food Sci Nutr. Oncogene 26: 7749-7758. 2019 Sep 10;11(9):2169. doi:10.3390/nu11092169. If you can inhibit this enzyme, however, it reduces inflammation, speeds up recovery time and keeps scarring to a minimum. These are involved in Cell Cycle Arrest CCA), Nucleotide Excision Repair (NER) and replacement by newly synthesized nucleotide strands. As an Amazon Associate, Easy Health Options may earn from qualifying purchases. Effects of Turmeric (Curcuma Longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytotherapy Research: PTR 30 (8): 124364. Kant et al. A limitation is that this study was conducted over four weeks, while most acne studies are conducted over an eight- to 12-week period.
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